A comprehensive archive of homœopathic materia medica

Article

PATHOGENESIS OF THYMULIN AND CLINICAL USE IN THE AIDS.- Dr P. Souk-Aloun

Sommaire
French

Methodology of Homoeopathy
(with 10 new provings). Dr P. Souk-Aloun.


PATHOGENESIS OF THYMULIN AND CLINICAL USE
IN THE AIDS.

SUMMARY : Short  pathogenesis of Thymulin and its use in the AIDS.

I. SHORT PATHOGENESIS.

    The Thymulin is a hormone secreted by the thymus; it has for main
function the maturation of the T lymphocyts and stimulation of the immune system.

    The professor  M.R. Bastide had demonstrated its action on the
immuno-deficient mouse. In its diluted and dynamised form, Thimulin is used by homoeopaths
in the prevention of recurrent ENT disorders of children.

MIND.

– Rush of ideas morning after rising (Man, 49, self-proving, taking Thymulin 30 CH,
  5 granules x2 times per day, third day).

RECTUM.

– Constipation (woman, tuberculous, HIV positive, after every taking of Thymulin 5 CH)

– Diarrhoea improved (woman, HIV positive, after 2 doses of  Thymulin 5 CH, 1
dose/2 weeks).

GENERALITIES.

– Adenitis increased in volume and becomes again painful (woman HIV positive, during
the first 3 months after every taken of Thymulin 5 CH, 1 dose/2 weeks).

– Adenitis decreased in volume (woman HIV positive, after the first 3 months of
Thymulin 5 CH, 1 dose/2 weeks).

– T4 Lymphocyts increased (2 women HIV positive with opportunistic infections)

II. A CASE OF INFECTION BY HIV:

    Woman about 28 years, see in consultation  2  March 1993.
She was singer in a Rock band, heroin abdict about 16, HIV positive at 20 years (1985);
the HIV contagion would be dated one year before. Currently, she get drunk on beer from
time to time, smoke about twenty cigarettes per day, but say doesn’t not take heroin no
more. On the sexual field, I suppose that she takes no particular precaution (1 voluntary
termination of pregnancy in 89, 1 pregnancy at term in 90).

    Concerning the follow-up treatments, one notes 6 months under
Zidovudine in 1987, with haematologic complications requiring the stopping; since she was
reticent to the allopathic therapeutic.  She was in the care of a unicist homeopath
in 1991-1992 (prescribed remedy: Anantherum muricatum), she had come to see me in 1993,
persuaded that her state became worse.

    On the mental field, she reserved enough (becomes violent and
arrogant after having drunk, but repenting quickly), sensitive, unsteady, enough
egocentric, suicidal (several suicide attempts: by phlebotomy after a break-up in 83, by
defenestration of the 2nd floor in 90), very anguished (but who would not be in her
situation?) especially when waiting for biologic exam results (opportunity for her to
drink some beer), depressive, tendency to be disappointed in love, feeling ill at ease
with strangers, difficulty to falling asleep. She often had dreams of water, of ocean,
erotic dreams.

    Physically she was enough small and thin (1,51 m,  about 45
kg), with the straight and brown hair, sensitive to cold; get dressed and maked up with
refinement.

    The family case history: a grandmother deceased by  septicaemia
about forty following a small injury of hand, a lot of arthritis; her father was
eczematous. In his personal case history: addictions (heroine, alcohol, tobacco, etc…),
suicide attempts after love disappointment (83), contagion by HIV certainly by exchange of
contaminated needles (84), B hepatitis (1985), scars of arms (cutaneous abrasion to erase
some tattoos), mouth candidiasis (1990 and before), diarrhoea by Cryptosporidies (since
1989, diagnosis in 1992), voluntary termination of pregnancy (1989), suicide attempt by
defenestration (1990), pregnancy and delivery of a girl HIV negative (October 1990).

    The examination shows some cervical adenitis, and in the left
pitarm; enlarged spleen, painful abdomen especially left side; furred tongue, dry mouth;
symptoms of spasmophilia.

    She complains about morning asthenia,  diarrhoea (first
occasional then continuous, disappearing  sometimes when she is with one of her
sisters with which she feels well); liquid stools as soon as she eats or drinks; 4 or 5
defecations/day. Chronic loose cough. Perspiration of armpits morning and night, moist
hands. Cramping pain of spleen area, aggravated afternoon and evening.

    The lymphocyts counts begin at 1990:

January 1990:    Lymphocyts: 1713
        T4: 646
            T8: 679

July 1990:
                                             
T4: 412            T8: 841
(pregnancy)

septembre1990:
                                   
T4: 411            T8: 632
(pregnancy)

November 1990: Lympho: 1400
            T4: 410
            T8: 615 (post-partum)
   

January 1991:    Lympho: 1400 
              T4: 492
            T8: 604

February 1991:  Lympho: 1600 
              T4: 512
            T8: 752 (Anantherum)

April 1991:
                                           
T4: 520 (Anantherum)

November 1991: Lympho: 1400            
T4: 410             T8: 615
(Anantherum)

October 1992:    Lympho: 1273
            T4: 390
            T8: 577

November 1992:
                                   
T4: 390

December 1992:
                                   
T4: 390            T8: 500

2 March 1993: first consultation: Thymulin 5 CHS, 1 dose globules (taken the following
day),

      Vitamins, Selenium.

3 March 1993:    Lympho: 1449
            T4: 425
          T8: 668
        T4/T8: 0,63

17 March 1993: feels better: Thymulin 5 CH 1 dose globule, Sarcolem, successively: Nux
vomica, Podophyllum, Gambosia (unaltered diarrhoea). Two days after the 2nd dose: pain and
swelling of ganglions of the left armpit.

29 March 1993: gain of weight (46 kg): Thymuline 5 CH 1 dose globules.

1 April 1993:        Lympho: 1352
            T4: 428
            T8: 590
          T4/T8: 0,72

15 April 1993: Thymulin 5 CH 1 dose globules, Dry yeast, 2 capsules x3 /day (diarrhoea
stopped).

7 April 1993: disappearance of the pain of spleen, ganglions of armpits seem to
decrease in volume: Thymulin 5 CH 1 dose globules.

6 May 1993: during one week: perspire the day, throbbing in the right eye then in the
right ear, nausea in the morning: Silicea 5 CH, Calcibronat. But she feels better, doesn’t
believe to the fatal exit of the disease.

6 May 1993:      Lympho: 1432
            T4: 475
            T8: 646
        T4/T8: 0,73

III.COMMENTARY:

    The biologic criteria  here is the count  of CD4 (or T4)
lymphocyts,  their number is a predicting data of the disease. The CD4 count decrease
about 70 units /year of infection by HIV. Lover than  50 CD4/mm3,  death is in
the short term. Of course, a follow-up on few months is little meaningful in this
affection. Besides, artefacts are possible. But faced with the despair of patients and
physicians confronted with the AIDS, this case is the testimony of the general
practitioner.

    In the related case, the CD4 fell until 1991. At that time the
patient was in the care of a homeopath that gave her Anantherum. This drug seemed to
provoke a rise of the CD4 during some months. Then the CD4 fall again.

    Thereafter I lost sight of  the patient (I had lectured her
seriously on her mindless behavior). In April 1995 I met her in the street; she is well,
and is in care with another homeopath.

    Anantherum muricatum (Andropogon or Cymbopogon muricatus, Andropogon
or Cymbopogon squarrosus, Vetiveria odorata, Vetiveria squarrosus, Cuscus grass, Vétiver
or Viti-vayr) is an aromatic and medicinal herb of India whose root is used to threat
fevers and abscesses. In Malaysia, one uses it against puerpueral fever. In Viêt Nam, its
decoction is reputed repulsive for the external parasites and is used to wash hairs. Its
very obstinate perfume enters in the composition of incenses of high quality. Anantherum
has been experimented by the Dr J.L. Houat; Lilienthal signals its use in skin diseases;
Clarke indicates it in abscesses, aphonia, boil, cancer, erysipela, glandular
inflammation, hydrophobia, sycosis, syphilis, convulsive or painful tic, tumors and
ulcers. One raises in the Guiding symptoms of Hering: cheerful  with disposition to
laugh and sing, sadness…, loathing to be in society; pain of the spleen; swelling of
ganglions of armpits and the chest (with tumor of the chest); glandular inflammation;
inflammation of spleen; and of course, a lot of symptoms of skin. Certainly it is a remedy
to know better.

    The prescription of Thymulin 5 CH is based on different tactics: the
CD4 is one of the indicators of the disease: the treatment aims to raise their number. We
know that Thymulin can contribute to this effect. The procedure is simple: Thymulin 5 CH,
1 dose globules morning on an empty stomach, once every 15 day; 1 count of CD4 lymphocyts
per month.

Sommaire